منابع مشابه
Ecstasy-induced toxicity in rat liver.
BACKGROUND/AIMS The aim of the present study was to examine the effects of single and repeated administration of 3,4-methylenedioxyme-thamphetamine (MDMA, "ecstasy") on rat liver. METHODS Animals were given an acute (20 mg/kg) and repeated (20 mg/kg, b.i.d., for 4 consecutive days) intraperitoneal dose of MDMA, and at various times after administration the hepatic and serum determinations wer...
متن کاملAgony and ecstasy: a review of MDMA effects and toxicity.
BACKGROUND Ecstasy is a recreational drug with an anecdotal reputation for safety. However, reports of adverse effects and fatalities have increased in the medical and popular press. METHOD Literature search and review. RESULTS Acute Ecstasy toxicity does not appear to be due to overdose and cannot be solely attributed to the nature of the usual ambient environment. Adverse effects include ...
متن کاملToxicity of drug abuse--amphetamine designer drugs (ecstasy): mental effects and consequences of single dose use.
MDMA (3,4-methylendioxymethamphetamine) is the most commonly used substance within the 'ecstasy' group of drugs. MDMA interferes with serotonin and catecholamine transporters in the central nervous system to increase monoamine synaptic levels and thereby mediate the majority of its central nervous effects. These range from wanted effects like euphoria, central nervous stimulation, and feeling o...
متن کاملToxicodynamics and long-term toxicity of the recreational drug, 3, 4-methylenedioxymethamphetamine (MDMA, 'Ecstasy').
The recreational drug, (+/-)3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), is a potent serotonin (5-HT) neurotoxin in animals. Whether humans who use MDMA incur 5-HT neural injury is unknown. The present studies utilized positron emission tomography (PET) in conjunction with the 5-HT transporter ligand, [11C]McN-5652 to assess the status of brain 5-HT neurons in human MDMA users. Like non...
متن کامل'Ecstasy' induced pneumomediastinum.
Two cases are reported of pneumomediastinum induced by the use of Ecstasy, a semi-synthetic hallucinogenic compound related to amphetamine and mescaline which has become established as a recreational drug in the UK since the late 1980s. Both cases recovered without incident, but it is important that the possible complications of this drug be publicised so that at risk subjects can be diagnosed ...
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ژورنال
عنوان ژورنال: Emergency Medicine Journal
سال: 1995
ISSN: 1472-0205,1472-0213
DOI: 10.1136/emj.12.1.74